Biological network motif detection: principles and practice
نویسندگان
چکیده
منابع مشابه
Biological network motif detection: principles and practice
Network motifs are statistically overrepresented sub-structures (sub-graphs) in a network, and have been recognized as 'the simple building blocks of complex networks'. Study of biological network motifs may reveal answers to many important biological questions. The main difficulty in detecting larger network motifs in biological networks lies in the facts that the number of possible sub-graphs...
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fanmod [6] is a tool for finding so-called networks motifs in a network, that is, it finds small vertex-induced subgraphs that occur significantly more often than in random networks. For a general introduction to the concept of network motifs, see [3, 2]. fanmod is able to search for network motifs of size between three and eight vertices. It can also analyze colored networks, allowing the user...
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Network motif detection is the search for statistically overrepresented subgraphs present in a larger target network. They are thought to represent key structure and control mechanisms. Although the problem is exponential in nature, several algorithms and tools have been developed for efficiently detecting network motifs. This work analyzes 11 network motif detection tools and algorithms. Detai...
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ژورنال
عنوان ژورنال: Briefings in Bioinformatics
سال: 2011
ISSN: 1467-5463,1477-4054
DOI: 10.1093/bib/bbr033